Weight loss has advantages in reducing cardiovascular risk factors and other obesity associated diseases.

Benefits of weight loss on health risks in obesity (Evidence Level B) Health Risk Benefits of 10 kg weight loss in a 100 kg subject
1. Blood Pressure
  • 10 mmHg reduction systolic BP
  • 20 mmHg reduction diastolic BP
  • Weight loss also reduces the need for medication in hypertensive patients
2. Lipids
  • 10% reduction in Total Cholesterol
  • 15% reduction in LDL-cholesterol
  • 30% reduction in Triglycerides
  • 8% increase in HDL-cholesterol
3. Diabetes
  • >50% reduction in risk of developing DM (Weight loss of 6.8 kg is associated with 58% reduction in incidence of diabetes, at 3 years in the Diabetes Prevention Programme)
  • 30-50% reduction in Fasting plasma glucose
  • 15% reduction in HbA1c
4. Osteoarthritis
  • Decrease BMI > 2kg/m2 associated with more than 50% decreased risk for developing osteoarthritis
5. Mortality
  • 20 –25% reduction all – cause mortality
  • 30 – 40% reduction diabetes related death
  • 40 – 50% reduction in obesity-related cancer death